Plasma
- Plasma is the liquid part of blood.
- Serum is the liquid that separates from clotted blood (plasma without clotting factors).
- Lymph is the fluid within lymphatic vessels (mostly plasma and white blood cells).
- The blood contains important proteins: albumin, globulins, and fibrinogen.
- Serum albumin makes up more than half of plasma proteins.
- Albumin is a major contributor to the osmotic pressure of plasma.
- Albumin is produced in the liver and transports fatty acids and some lipid-soluble hormones and drugs.
- Globulins make up about 35% of plasma proteins, including immunoglobulins (antibodies) and transport proteins.
- Fibrinogen is converted to insoluble fibrin strands by thrombin during blood clotting.
- Soluble organic nutrients in the blood include glucose, fatty acids, amino acids, and wastes (such as urea).
- Triglycerides and cholesterol are not soluble in plasma, so are carried with lipoproteins (lipid/protein complexes).
- The major buffer in blood is bicarbonate, with a pH between 7.35 and 7.45.
- The major ions in blood are sodium and chloride.